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TVIS30000916
Basic Information
VIS ID
TVIS30000916
Fusion event
HIV-KIF3B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
30911333/32323530 (Hg38)
End
30911646/32323530 (Hg38)
Orient
+
Location type
Intronic
Target gene
KIF3B
miRNAs that regulate target gene
hsa-mir-324-5p
;
hsa-mir-222-3p
;
hsa-mir-10a-5p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-181d-5p
;
hsa-mir-646
;
hsa-mir-4424
;
hsa-mir-4682
;
hsa-mir-8077
;
hsa-mir-1292-5p
;
hsa-mir-4471
;
hsa-mir-8059
;
hsa-mir-874-3p
;
hsa-mir-146b-3p
;
hsa-mir-6799-3p
;
hsa-mir-3173-5p
;
hsa-mir-7976
;
hsa-mir-4468
;
hsa-mir-4646-5p
;
hsa-mir-204-3p
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-410-3p
;
hsa-mir-6750-3p
;
hsa-mir-1226-5p
;
hsa-mir-129-5p
;
hsa-mir-1304-5p
;
hsa-mir-1914-3p
;
hsa-mir-3184-5p
;
hsa-mir-423-5p
;
hsa-mir-4294
;
hsa-mir-4716-3p
;
hsa-mir-4723-5p
;
hsa-mir-5194
;
hsa-mir-5698
;
hsa-mir-6734-5p
;
hsa-mir-6738-5p
;
hsa-mir-6794-5p
;
hsa-mir-6834-5p
;
hsa-mir-6870-5p
;
hsa-mir-7111-5p
;
hsa-mir-8055
Nearest miRNA
hsa-mir-103a-2/Upstream/85683; hsa-mir-1-1/Downstream/1725589;
Nearest TSS
ENST00000382410/Upstream/45866;
ENST00000612444/Downstream/31523;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/45542
,
chr20-CpG: 104/Downstream/34314
Target sequence
CTGGGACTACTCGAGTAGTGAGCCACCACGCCCAGCCAATTCTTTTTATTTTTAAAAATATTTTTCAGCCGAGCATGGTGTCTCGTACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCATGAGGTCAGGAGTTCAAGACCAGCCTGGCCAAGATGGTGAAACCCCCATCTCTACTAAAAATACAAGAATTAGCTGGGTGTGGTGGCGGGCGCCTGTAATCTCAACTACTCGGGAGGCTGAGGCAG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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