Basic Information
VIS ID
TVIS30000918
Fusion event
HIV-LINC00623 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
144328426/145203542 (Hg38)
End
144328766/145203542 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA1F
Target gene
LINC00623
Nearest miRNA
hsa-mir-101-1/Upstream/28108814; hsa-mir-1182/Downstream/647045;
Nearest TSS
ENST00000473358/Upstream/107542; ENST00000618589/Downstream/38582;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/34514, chr1-CpG: 123/Downstream/11291
Target sequence
ACCACCCTAACTGATTTGAAAGTCTACAATTTTCTCAATTTAAAATGGTATTTATTTGTAACATGTACTATTATTGAATAACAATTTCTAATTAAAAAACTACGCTAGTTTTCTGCCTATGGAGAAGCCACCTTTTTATTCTTTTACTTTCTTAATAAGCTTGCTTTCACTTAAAAAAAAAATCTACCCTACATATACACAAAAGTTAAAAAGCAGCAATATTGTACATTGGTCAGTATAAATGCATGCAGTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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