Basic Information
VIS ID
TVIS30000927
Fusion event
HIV-PRKCH integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.1
Reference genome
End
61865742/61398201 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-208a/Upstream/749490; hsa-mir-1185-1/Downstream/2696823;
Target sequence
ACCACAATACCACAATCACACCTAAATAACATCAACAATTCTGTAATATCCTCACAGATCCAGGCACGGTTTCCATTTCTTCACTTGCCTCCTGGGAGTTAATGTTTCTTTTATAATTTGTGTTTGAATTGGGATAAAATGTGGCCCATATATTGCAAATGATTAATATGCCTCTCTCTTGTTACTTTGGTTCTCTTTCCTTTACTTTTTTCTTCCAATGTTTGGTAGAAGAAACCAAGTCTCTTTTCCTGTAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate