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TVIS30000930
Basic Information
VIS ID
TVIS30000930
Fusion event
HIV-RBL1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
35642488/37014085 (Hg38)
End
35642813/37014085 (Hg38)
Orient
-
Location type
Intronic
Target gene
RBL1
miRNAs that regulate target gene
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-580-3p
;
hsa-mir-526b-5p
;
hsa-mir-3646
;
hsa-mir-3662
;
hsa-mir-6806-5p
;
hsa-mir-5685
;
hsa-mir-4690-3p
;
hsa-mir-4717-5p
;
hsa-mir-449c-5p
;
hsa-mir-34b-5p
;
hsa-mir-2682-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-6815-3p
;
hsa-mir-6882-3p
;
hsa-mir-22-3p
;
hsa-mir-646
;
hsa-mir-892b
;
hsa-mir-193b-3p
;
hsa-mir-193a-3p
;
hsa-mir-5089-5p
;
hsa-mir-6878-3p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-6778-3p
;
hsa-mir-4707-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-212-5p
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
;
hsa-mir-186-3p
;
hsa-mir-6838-3p
;
hsa-mir-6507-3p
;
hsa-mir-150-5p
;
hsa-mir-5698
;
hsa-mir-8057
;
hsa-mir-143-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6722-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-6499-3p
;
hsa-mir-5693
;
hsa-mir-6813-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1559988; hsa-mir-1-1/Downstream/1502478;
Nearest TSS
ENST00000382410/Upstream/62184;
ENST00000598590/Downstream/53970;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/62037
,
chr20-CpG: 57/Downstream/81462
Nearest cancer related gene
RBL1
(TSG, No orient, 0)
Target sequence
ATAATGAACTCAGGAATTCTGGCACTCAAAAAGAGAGAACACAGTGGCTTACATCTACAATCCCAGCACTTTGGGAGGCCAAGCCAGGAGGGTGGCTTGAACCCAGGAGTTCAAGACCATTGTGGGTAACATAGTGACAGCCTATTGCTACAAAAAATTTTTTAAAATAGCCACACATGGTGGTGGGCTTCTGTAGTCCAAGCTACTCAGGAGGCTGAATTGGGAGGTTGGCTTGAGCCCAGGATGTCAAGGCTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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