Basic Information
VIS ID
TVIS30000930
Fusion event
HIV-RBL1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
End
35642813/37014085 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/1559988; hsa-mir-1-1/Downstream/1502478;
Nearest cancer related gene
RBL1(TSG, No orient, 0)
Target sequence
ATAATGAACTCAGGAATTCTGGCACTCAAAAAGAGAGAACACAGTGGCTTACATCTACAATCCCAGCACTTTGGGAGGCCAAGCCAGGAGGGTGGCTTGAACCCAGGAGTTCAAGACCATTGTGGGTAACATAGTGACAGCCTATTGCTACAAAAAATTTTTTAAAATAGCCACACATGGTGGTGGGCTTCTGTAGTCCAAGCTACTCAGGAGGCTGAATTGGGAGGTTGGCTTGAGCCCAGGATGTCAAGGCTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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