Basic Information
VIS ID
TVIS30000933
Fusion event
HIV-SLC26A11 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
78206059/80232260 (Hg38)
End
78206284/80232260 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC26A11
Nearest miRNA
hsa-mir-10226/Upstream/133383; hsa-mir-1250/Downstream/187158;
Nearest TSS
ENST00000595228/Upstream/4408; ENST00000575019/Downstream/15954;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11105, chr17-CpG: 128/Downstream/27882
Target sequence
GCCAAGAATTTGAGACCAGGCTGGCCAACATGGTGAAACCTCATTGCTACTAAAAACACAAAAATTAGCTGGGCTTGGTGGTGCAAGCCTGTAATTCCAGCTACTTGGGAGGCTGAGGCACAACAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCACGCCATTGCACTCCAGCCTGGGCAACAGAGAGAGATTCTGTCTCAAAAAAAAAAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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