Basic Information
VIS ID
TVIS30000948
Fusion event
HIV-chr3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p23
Reference genome
GRCh37/hg19
Start
31351646/31310154 (Hg38)
End
31352590/31310154 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/148367; hsa-let-7g/Downstream/1196129;
Nearest TSS
ENST00000440867/Upstream/415389; ENST00000462235/Downstream/222484;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/415381, chr3-CpG: 196/Downstream/221656
Nearby gene
MIR466(No orient, 148367)
Target sequence
GTTGAGAAAATTGGCATTTGGCAACCATCCAACCTGTCTCCAGCTTCTCCTTGCTGCGTATATTATTCTGTGTAGCTTATATTTAAACAATGGGACAATGTGGTGAGGGGCTGGTCTGTAGTTTAGATCTCACTCCCTTCACTTCAAATGATACAGTCTGTTGGAGCCAGTTATCTAGGTCTTTCCTCTTCTTATTGTATGCATGTTAGTTGCGTGTTTTAAGTTTTTCACAATATGTTGGAACGAAGATAATTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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