Basic Information
VIS ID
TVIS30000949
Fusion event
HIV-LOC105377781 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
2107263/2159338 (Hg38)
End
2108010/2159338 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377781
Nearest miRNA
hsa-mir-3674/Upstream/82698; hsa-mir-10400/Downstream/4462786;
Nearest TSS
ENST00000518652/Upstream/15989; ENST00000633673/Downstream/336184;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/28899, chr8-CpG: 35/Downstream/22322
Nearby gene
MYOM2(No orient, 13883)
Target sequence
GTCAGCAAACTCCTTGAGATGTGAGAAAATAAAACTCTTTTTAAGCAATGGTAAGTTTTGTTACCTAGTTACTTATGGGCAGGCATATCGTAACTGATATGGAATTTGGTAACAAGAAGAGACGTGCTCCAAGAAACAGACCCTAAATTGTGGAAACAGGTGCCAGCGTGTGGCTCAGTGGAAAAGGCAGGGCAGCAGGTGTCAAAGAGAGGAACAGCCCCCCCATTCCTTCTCGAAGGAAAGAGGGATGCTTCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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