Basic Information
VIS ID
TVIS30000950
Fusion event
HIV-MTCO2P20 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36569881/36173833 (Hg38)
End
36570819/36173833 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
MTCO2P20
Nearest miRNA
hsa-mir-1286/Upstream/837034; hsa-let-7a-3/Downstream/113014;
Nearest TSS
ENST00000624155/Upstream/7656; ENST00000475519/Downstream/28044;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/107470, chr22-CpG: 24/Downstream/148572
Nearby gene
APOL3(No orient, 7656)
Target sequence
TATACGACCAGACCTTTACTACAGACAATGCCCAGAAATCTGCAGATCCAACCATGGCTTTATACCCATTGTTCTTGAACTAGTCCCCCTAAAGCACTTCGAAAATTGGTCAGCCTCTGTATCATAATATCACTGTGAAGCTAATTAGCATTAACCTTTTATGTTAAAGACCGAGAGCCAGGATTTCTCCACATTAAAATGTCCCAACTAAACACATCTACATTATTTACTATGGTTTTATGTATAATCATATCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate