Basic Information
VIS ID
TVIS30000951
Fusion event
HIV-LOC105371449 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
154893160/154920684 (Hg38)
End
154893902/154920684 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
LOC105371449
Nearest miRNA
hsa-mir-101-1/Upstream/726941; hsa-mir-1182/Downstream/55009;
Nearest TSS
ENST00000473358/Upstream/50404; ENST00000604546/Downstream/16307;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/148296, chr1-CpG: 79/Downstream/15802
Nearby gene
PMVK(No orient, 4048)
Target sequence
ATATGTAGTTATTATATTTTAATTATAGCTCAATAAAGTTGTTTAGAAATATAATAATAAATTTTTAAAGAGGCTGTTAGTGTTACAAATCATGACTAAAATAACATATACATACATTCATGGGTGGGTAATAAATAAAAAAAGAAGAAGTAGTAAAATAACAGACACATAATATTAAAAATAACTTGGCCAGGCATGGTGGCCCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGAAGCTTCGTTTGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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