Basic Information
VIS ID
TVIS30000959
Fusion event
HIV-chr9 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
90105965/87491050 (Hg38)
End
90106331/87491050 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/3521193; hsa-let-7a-1/Downstream/1254786;
Nearest TSS
ENST00000422679/Upstream/342406; ENST00000470267/Downstream/6178;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/342198, chr9-CpG: 145/Downstream/6549
Nearby gene
DAPK1(No orient, 6178)
Nearest cancer related gene
DAPK1(TSG, No orient, 6178)
Target sequence
GCACATGCTAGCAAAATGAGTGACACATACACTACCATGAGGCACCTCCATGACAATTCAGTTAGGAACCTGATTGACATTCTGAGCCTTGAGTTTTGCAAATGCTGTTTAGTGTTACCAATCTTTTGCTTCAGGTAGTGACAGAACCTAAATGAAATTGGTCCAGGCATAAAAGAAATTAGGCTAAAGGCAAAAGTAAACCTGTAATGCCAGATCACTGGTCAGTGACTTGTAAGTGCTTATTTGCACACTGCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate