Basic Information
VIS ID
TVIS30000964
Fusion event
HIV-LINC02725 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
127966178/128096283 (Hg38)
End
127966655/128096283 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02725
Nearest miRNA
hsa-let-7a-2/Upstream/1107741; hsa-mir-4697/Downstream/426107;
Nearest TSS
ENST00000527297/Upstream/825221; ENST00000609911/Downstream/84144;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1092369, chr11-CpG: 20/Downstream/355483
Nearby gene
ETS1(No orient, 362478)
Target sequence
TGGGTGCCCACCTGTACTGGTGAAGGCAGATGATCTTAACACAGTCTACTCATTCAAGTGCTAATCTCTTCCAGAAACACCCTCACATACGTGTCCAGAATAAAATTTTACTAGTTTTCTGGGGATCCCTTAGCTCAGTCAAGTTGGCATATAAAATTAATAATTACAGATCTACCTCTTATCAATTTGGCTTATGTATCTCCTTAAATCATACCTAATCTCCAGATAAAGATAACAATAACATCGTGATTTCAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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