Basic Information
VIS ID
TVIS30000966
Fusion event
HIV-TEX28P2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
153443831/154178343 (Hg38)
End
153444461/154178343 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
TEX28P2
Nearest miRNA
hsa-let-7f-2/Upstream/158354; hsa-mir-1184-1/Downstream/271977;
Nearest TSS
ENST00000429181/Upstream/25401; ENST00000595330/Downstream/4253;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/41144, chrX-CpG: 32/Downstream/117045
Nearby gene
OPN1MW(No orient, 4254)
Target sequence
CTGCCTCCTGGGTTCAAGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCACCACCATGCCCAGTTAATTTTTTGTATTTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAGGTTAGCCTCAAACTCCTGACGTCAGGTGATCCACCCGCCTTGGCCTCCCAAAATGCTGGGATTACAGGCGTGTGAGCCACCGCGCCCGGCCTGGATACTTTCTTTAGCTCCTCTGTACAATTTACC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate