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TVIS30000975
Basic Information
VIS ID
TVIS30000975
Fusion event
HIV-CLIC5 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
45915263/45947526 (Hg38)
End
45915531/45947526 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
CLIC5
miRNAs that regulate target gene
hsa-mir-628-5p
;
hsa-mir-6807-5p
;
hsa-mir-8077
;
hsa-mir-7160-5p
;
hsa-mir-4663
;
hsa-mir-4480
;
hsa-mir-4251
;
hsa-mir-539-5p
;
hsa-mir-3691-3p
;
hsa-mir-5680
;
hsa-mir-1252-3p
;
hsa-mir-607
;
hsa-mir-3686
;
hsa-mir-6749-3p
;
hsa-mir-642a-5p
;
hsa-mir-6826-3p
;
hsa-mir-3671
;
hsa-mir-3182
;
hsa-mir-4469
;
hsa-mir-1237-3p
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
;
hsa-mir-483-3p
;
hsa-mir-335-3p
;
hsa-mir-5096
;
hsa-mir-548au-3p
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-34a-5p
;
hsa-mir-6868-5p
;
hsa-mir-8073
;
hsa-mir-221-5p
;
hsa-mir-6765-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-4282
;
hsa-mir-548c-3p
;
hsa-mir-4753-3p
;
hsa-mir-5579-3p
;
hsa-mir-4279
;
hsa-mir-3156-3p
;
hsa-mir-6802-3p
;
hsa-mir-6837-3p
;
hsa-mir-6754-3p
;
hsa-mir-412-3p
;
hsa-mir-6845-3p
;
hsa-mir-532-3p
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-4301
;
hsa-mir-500b-3p
Nearest miRNA
hsa-mir-10398/Upstream/749756; hsa-mir-10524/Downstream/6196823;
Nearest TSS
ENST00000381078/Upstream/9925;
ENST00000321037/Downstream/68020;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/283449
,
chr6-CpG: 72/Downstream/67614
Target sequence
ACTGCTTCCACTTTCCACTTCCTAATGATCATGACGGAAGCCCCCACTCCTGAGTGCCAGTGTTACTTCTAAGAGGGAAAATGTTAACTGCGTCATGAACTTTCCTCTATGGGTCTCCCAGGCAAAGTCTAAACTCTAGTTATTGAAAAGAGCATTTTTTTTCATGTGGGATTTCAAATCAGTGCTAGCAATGAGGTTGAGTCCCGGGGAGGGGGATGGAGTCTGGGCTCCCTCAGGGCACTTCCAGTGAAGTGG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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