Basic Information
VIS ID
TVIS30000978
Fusion event
HIV-FUBP3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.12
Reference genome
GRCh37/hg19
Start
133494118/130618731 (Hg38)
End
133494688/130618731 (Hg38)
Orient
-
Location type
Intronic
Target gene
FUBP3
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-let-7a-1/Upstream/377243; hsa-mir-126/Downstream/7566;
Nearest TSS
ENST00000422679/Upstream/37636; ENST00000487406/Downstream/1683;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/38622, chr9-CpG: 632/Downstream/40416
Target sequence
AAATATACAGTTTTAAAATTTAAAAATCACTAAAACCCGTTAAGTTAAAATTATTTTCCTGCAAATTTATGGGACATTAATGATATATTCTTTGCTTGGGGTTTTTCCCTACAAAAGACACCATCAAAGGCTGTGATAGAAAAAGAAGGCCTCTGAGGGAGGGCAGCCAAGAGGCAGGCACTCTGTGGCCGCCCACAGGCCTGGATCCAACACCATCACAGTACTGGAGCCCACGGCCGGACGCTGAGCAGGGTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate