Basic Information
VIS ID
TVIS30000981
Fusion event
HIV-KIF1B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
End
10341154/10280459 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/313001; hsa-mir-101-1/Downstream/1748699;
Nearest cancer related gene
KIF1B(TSG, No orient, 0)
Target sequence
GTTGCTTCAAGACAGTTTGAAAACCACCATCTGCAAATACAGAACATAGGGCAACAAGCAAAGAGGCATCTTTTAAAAGGGGGATAGGGATTAGAGCAAAAAATTAGCCATTGGGAGAAAAGACCAGGATGGACAGAGTTTAGGTCCAATGGTCACATGCAAGCCCTAAAAGGAATAAAGAGAAATAGATCAAAATGGAAACTGAGAAGGAGTCAGGGCTGCTTTCCCTCAGGAATACAGAATTAAAACTTAGTC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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