Basic Information
VIS ID
TVIS30000989
Fusion event
HIV-TBCD integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80715498/82757622 (Hg38)
End
80715918/82757622 (Hg38)
Orient
-
Location type
Intronic
Target gene
TBCD
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-10226/Upstream/89315;
Nearest TSS
ENST00000595228/Upstream/5464; ENST00000572984/Downstream/38473;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/4655, chr17-CpG: 17/Downstream/22044
Target sequence
ACAACAAGTGTTAATATTCCATGATCCACTCTGGAAAGAGGTCTGGCAAGAATAAAGGCATTTAACTACAGGTCCAACGTTGTTACTTGAAGAGATATAAAAACACCACCCGCTACCTTGTGAGCAGTGACCACATCTGTTTCCTGGGAACCAGCGCTCACACACAGGAACTCCAGGAACCCAAGACCTCCTATAAGATATGGCCTGGGGAGCCCACTGCCTGCCACGCCATCCAGCATGGCTAGCCCCTCCACC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate