Basic Information
VIS ID
TVIS30000997
Fusion event
HIV-CLEC4A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
8255862/8103266 (Hg38)
End
8255998/8103266 (Hg38)
Orient
+
Location type
Intronic
Target gene
CLEC4A
Nearest miRNA
hsa-mir-141/Upstream/1139075; hsa-let-7i/Downstream/1136201;
Nearest TSS
ENST00000382841/Upstream/7988; ENST00000641376/Downstream/20366;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/20842, chr12-CpG: 42/Downstream/76926
Nearby gene
NECAP1(No orient, 5489)
Target sequence
CTTATAAAGTCCAAAATATAATTTCATCTTCAACTCAGTTTTCCCATTGACTCACAATGTGCTTTAACAAACTTAAGAACTACTAGTTGTTTTCTTTGTTTCTTTCTGTTGTTTTTTTTTTTTTTTTTTTTTTTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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