VISDB Viral Integration Site DataBase

VIS ID

TVIS30000999

Fusion event

HIV-ARHGEF18 integration

Validated

Yes

Detection method

QiaQuick PCR and Sequencing

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.2

Reference genome

Start

End

7417638/7352537 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-24-3p ; hsa-mir-221-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-1469 ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-3135a ; hsa-mir-4632-3p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-6857-3p ; hsa-mir-4329 ; hsa-mir-4446-3p ; hsa-mir-9500

Nearest miRNA

hsa-mir-1227/Upstream/615759; hsa-let-7e/Downstream/264902;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/57440, chr19-CpG: 65/Downstream/42356

Nearby gene

ARHGEF18(No orient, 42568)

Target sequence

GCTAACACTGTGAAACCCCGTCTCTACTGAAAATACAAAAAATTAGCCGGGCGTGGTGGCAGGCACCTGTATTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCCAGATCATGCCACTGCACAACAGCCTGGGTGACAGAGTGATATTCCATCTCAAAAAAAAAAAAAAAA