Basic Information
VIS ID
TVIS30001000
Fusion event
HIV-CCND2-AS1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
4370894/4261728 (Hg38)
End
4371667/4261728 (Hg38)
Orient
-
Location type
Intronic
Target gene
CCND2-AS1
Nearest miRNA
hsa-mir-3649/Upstream/2601348; hsa-let-7i/Downstream/2701971;
Nearest TSS
ENST00000382841/Upstream/235743; ENST00000541542/Downstream/12044;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17665, chr12-CpG: 379/Downstream/7508
Nearby gene
CCND2-AS1(No orient, 122127)
Target sequence
GTCAGGAGTTTGAGACTAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAAAACAAAAATTAGTTGGGTGTGGCGGCGCAGCCTGTAGTCCCAGCTGCGTGGGAGGCTGAGGCAGGAGAATCACTTGAACTGGGAGGTGAAGGTTGCAGTGAGCTGAGAACACGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTGCGTCTCAAAAGAAAAGACAGATTTCTGTTTGTATAATGAGCTTCCTCTGC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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