Basic Information
VIS ID
TVIS30001001
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
12937696/12797570 (Hg38)
End
12938437/12797570 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3125/Upstream/60126; hsa-mir-10b/Downstream/6550859;
Nearest TSS
ENST00000437798/Upstream/79332; ENST00000434509/Downstream/740103;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/78677, chr2-CpG: 248/Downstream/1834683
Nearby gene
TRIB2(No orient, 54838)
Nearest cancer related gene
TRIB2(OG, No orient, 54838)
Target sequence
GTTATGTGGGCTCTATTTTTTTTTACATATTCAGATGATGTTCCTGAGACTTAGAGAAGTTAAGTAATTAGTCAACTTCCCATAGTTTGAAACTGATGGATCCAGAATTTGAACCAGGGTCTGTCTGAAACCAGAGTCTAAGTCCTGAAACATTTTGTTGAATAACTCCTGTTTCTGCCTAAACTTATTTGTTATTTAGTGATAGTCAAAGCTGAATAGGTCTGTGCATAATCAGATTCCAGGTAAAACACATCT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate