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TVIS30001023
Basic Information
VIS ID
TVIS30001023
Fusion event
HIV-RICTOR integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
39060984/39060882 (Hg38)
End
39061824/39060882 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
RICTOR
miRNAs that regulate target gene
hsa-mir-218-5p
;
hsa-mir-335-5p
;
hsa-mir-155-5p
;
hsa-mir-31-3p
;
hsa-mir-18a-5p
;
hsa-mir-34a-5p
;
hsa-mir-6747-5p
;
hsa-mir-3124-3p
;
hsa-let-7c-5p
;
hsa-mir-16-5p
;
hsa-mir-142-3p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-6769b-5p
;
hsa-mir-6769a-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-654-5p
;
hsa-mir-541-3p
;
hsa-mir-7110-5p
;
hsa-mir-6842-5p
;
hsa-mir-6752-5p
;
hsa-mir-5010-5p
;
hsa-mir-4525
;
hsa-mir-7111-5p
;
hsa-mir-6870-5p
;
hsa-mir-4723-5p
;
hsa-mir-5698
;
hsa-mir-6825-5p
;
hsa-mir-625-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-8069
;
hsa-mir-8062
;
hsa-mir-8079
;
hsa-mir-1245a
;
hsa-mir-6841-5p
;
hsa-mir-6732-5p
;
hsa-mir-384
;
hsa-mir-3685
;
hsa-mir-6509-5p
;
hsa-mir-202-5p
;
hsa-mir-337-3p
;
hsa-mir-3160-5p
;
hsa-mir-3927-5p
;
hsa-mir-500b-5p
;
hsa-mir-362-5p
;
hsa-mir-128-3p
;
hsa-mir-153-5p
Nearest miRNA
hsa-mir-10397/Upstream/503321; hsa-mir-103a-1/Downstream/14890622;
Nearest TSS
ENST00000502646/Upstream/88921;
ENST00000603514/Downstream/13507;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/214508
,
chr5-CpG: 139/Downstream/12897
Target sequence
AACCCCACCTCTCTCTCTCATAATACCTATATGATCTTGGGCTAGTTAGGCATCGCCCCATTTTCCTCATCAGTTACACAGGTGTATTAATACATATTCTCCTAAGTATGTAGGAAGACAATGAGAATTTAAGTAATGTTTTTAACACACTCCCCAACATACATTATTCAAAATATGGCAGCTGCTGCTACTATTTCTTGTGTTCAAAGACGATTAAACATTTACCAATTAGAACAATGCTGGACACATAACCAG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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