Basic Information
VIS ID
TVIS30001039
Fusion event
HIV-LOC105372790 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
35422960/34050660 (Hg38)
End
35423373/34050660 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372790
Nearest miRNA
hsa-let-7c/Upstream/499932; hsa-mir-3197/Downstream/1670055;
Nearest TSS
ENST00000624081/Upstream/81141; ENST00000381151/Downstream/22564;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/134756, chr21-CpG: 151/Downstream/22127
Target sequence
GGTTGCATGGAGCAACATGAAGAAATCTCCAAAAATGATTTTGAGTGAAAGAAACCAAGCACAAAAGAAGGTGTACTGAAAGATTCCATTTATATGAAATTCAAAAAGCAAAACTAAACTCTAATATTTAAGAATACAAGTTGTGATGGTAAAACTGTCTTTTAAAAAATCAGGGAAATGACTTCCATAAAAATCAGGGTAGTGGCTACTTTAATCAGAGAGGGATGGTATGGTGATTGGAATACAGAGGAGGTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate