Basic Information
VIS ID
TVIS30001046
Fusion event
HIV-CMTM7 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32459307/32417815 (Hg38)
End
32459792/32417815 (Hg38)
Orient
-
Location type
Intronic
Target gene
CMTM7
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-12127/Upstream/1256028; hsa-let-7g/Downstream/88468;
Nearest TSS
ENST00000440867/Upstream/25776; ENST00000464689/Downstream/31700;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/15852, chr3-CpG: 26/Downstream/49958
Target sequence
CAGAATATACAAACAATACTCAAAACCTAAAAATAAAAAACCAACAAGCCTATTTTTAAAAATGGGCAAAAAATGTGAATAGATACTTCACCAAAGAGGCTATGTGGATGGCAAATAAGCACATGAAAAGATGTTCAACATTATAGTCTTTAGGGAAATGGAAATTAAAACCACAATAAGGACAGGCGCGGTGGCTCGCAACTGTAATCCCAGCACTTTGGGAGGCTGACGTAGGTGGAGCTCTTAAGCCCAGGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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