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TVIS30001050
Basic Information
VIS ID
TVIS30001050
Fusion event
HIV-LRRC8A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
131660408/128898129 (Hg38)
End
131660638/128898129 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRC8A
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-33a-5p
;
hsa-let-7b-5p
;
hsa-mir-149-5p
;
hsa-let-7e-5p
;
hsa-mir-191-5p
;
hsa-mir-1305
;
hsa-mir-607
;
hsa-mir-1250-3p
;
hsa-mir-330-3p
;
hsa-mir-6715a-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-4804-5p
;
hsa-mir-184
;
hsa-mir-4719
;
hsa-mir-4694-3p
Nearest miRNA
hsa-let-7a-1/Upstream/505415; hsa-mir-12126/Downstream/971476;
Nearest TSS
ENST00000422679/Upstream/13134;
ENST00000492784/Downstream/14615;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/15659
,
chr9-CpG: 80/Downstream/9474
Target sequence
CTTTGAACATTTCCTCTTGTTATCAAGTGTTTTGTTCTAATGCACTTTTGGGATTGCATAGTATTCCCTTATCTGATCATTGAGTATGTTTTTTGTTTGTTTGTTTTGTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGGGCAGTGGTGCGATCTTAGCTCACTGCAACCTCCACCACCTGGGTTCAAGCAATTCTCCTGCGTCAGCCTCCCAAGTAGTTGATCCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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