Basic Information
VIS ID
TVIS30001053
Fusion event
HIV-PDZD8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.11
Reference genome
End
119103154/117343099 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-151a-5p ; hsa-mir-130b-3p ; hsa-mir-425-5p ; hsa-mir-218-5p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-3618 ; hsa-mir-601 ; hsa-mir-3160-5p ; hsa-mir-4424 ; hsa-mir-139-5p ; hsa-mir-4797-5p ; hsa-mir-5003-3p ; hsa-mir-6862-5p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-545-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-7850-5p ; hsa-mir-4529-3p ; hsa-mir-4520-2-3p ; hsa-mir-4535 ; hsa-mir-4776-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-6740-5p ; hsa-mir-659-5p ; hsa-mir-492 ; hsa-mir-6861-3p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-4490 ; hsa-mir-4307 ; hsa-mir-526b-5p ; hsa-mir-4684-5p ; hsa-mir-7111-3p ; hsa-mir-1283 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-2116-3p ; hsa-mir-4713-5p ; hsa-mir-532-3p ; hsa-mir-3163 ; hsa-mir-150-5p ; hsa-mir-323a-3p ; hsa-mir-548c-3p ; hsa-mir-25-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-4766-3p ; hsa-mir-202-3p ; hsa-mir-4272 ; hsa-mir-6074 ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-mir-98-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-mir-6755-3p ; hsa-mir-223-3p ; hsa-mir-4697-3p ; hsa-mir-4328 ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-4327 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4728-5p ; hsa-mir-490-3p ; hsa-mir-5694 ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7851-3p
Nearest miRNA
hsa-mir-107/Upstream/175325; hsa-mir-202/Downstream/2034873;
Target sequence
ACTATCAGGATTTGAGTATGTGTTGCGCTGATTTACAAAGAGTTAACACTAAAACTGAAATAAACACTTAGAAAATATCAATGGCCTACTATAGTTTATACTGAAAGACACTAATAGAGGGGGTTAAATGCTGTTTTATGTTTTCCCAGTAAGTAAGATTAAAGAAAAAAATTTTAAGGAAATGTTAAGTAGGGACACAGGCGATGCTCAGTGCTTTTCTCCTGTTTCTAAACTAGTATGGAAAGCAGAAAGCCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate