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TVIS30001053
Basic Information
VIS ID
TVIS30001053
Fusion event
HIV-PDZD8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.11
Reference genome
GRCh37/hg19
Start
119102610/117343099 (Hg38)
End
119103154/117343099 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
PDZD8
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-151a-5p
;
hsa-mir-130b-3p
;
hsa-mir-425-5p
;
hsa-mir-218-5p
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-3618
;
hsa-mir-601
;
hsa-mir-3160-5p
;
hsa-mir-4424
;
hsa-mir-139-5p
;
hsa-mir-4797-5p
;
hsa-mir-5003-3p
;
hsa-mir-6862-5p
;
hsa-mir-3945
;
hsa-mir-4253
;
hsa-mir-545-3p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-7850-5p
;
hsa-mir-4529-3p
;
hsa-mir-4520-2-3p
;
hsa-mir-4535
;
hsa-mir-4776-5p
;
hsa-mir-655-3p
;
hsa-mir-374c-5p
;
hsa-mir-6740-5p
;
hsa-mir-659-5p
;
hsa-mir-492
;
hsa-mir-6861-3p
;
hsa-mir-631
;
hsa-mir-3661
;
hsa-mir-4490
;
hsa-mir-4307
;
hsa-mir-526b-5p
;
hsa-mir-4684-5p
;
hsa-mir-7111-3p
;
hsa-mir-1283
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-4325
;
hsa-mir-7703
;
hsa-mir-2116-3p
;
hsa-mir-4713-5p
;
hsa-mir-532-3p
;
hsa-mir-3163
;
hsa-mir-150-5p
;
hsa-mir-323a-3p
;
hsa-mir-548c-3p
;
hsa-mir-25-3p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-4766-3p
;
hsa-mir-202-3p
;
hsa-mir-4272
;
hsa-mir-6074
;
hsa-mir-3908
;
hsa-mir-4703-5p
;
hsa-mir-3942-5p
;
hsa-mir-5582-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-let-7e-5p
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-mir-98-5p
;
hsa-let-7a-5p
;
hsa-let-7b-5p
;
hsa-mir-6755-3p
;
hsa-mir-223-3p
;
hsa-mir-4697-3p
;
hsa-mir-4328
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-25-5p
;
hsa-mir-30b-3p
;
hsa-mir-3192-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-4327
;
hsa-mir-4537
;
hsa-mir-455-3p
;
hsa-mir-4728-5p
;
hsa-mir-490-3p
;
hsa-mir-5694
;
hsa-mir-6087
;
hsa-mir-6499-3p
;
hsa-mir-6516-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-7851-3p
Nearest miRNA
hsa-mir-107/Upstream/175325; hsa-mir-202/Downstream/2034873;
Nearest TSS
ENST00000439456/Upstream/24121;
ENST00000549104/Downstream/31382;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/101080
,
chr10-CpG: 198/Downstream/31193
Target sequence
ACTATCAGGATTTGAGTATGTGTTGCGCTGATTTACAAAGAGTTAACACTAAAACTGAAATAAACACTTAGAAAATATCAATGGCCTACTATAGTTTATACTGAAAGACACTAATAGAGGGGGTTAAATGCTGTTTTATGTTTTCCCAGTAAGTAAGATTAAAGAAAAAAATTTTAAGGAAATGTTAAGTAGGGACACAGGCGATGCTCAGTGCTTTTCTCCTGTTTCTAAACTAGTATGGAAAGCAGAAAGCCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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