Basic Information
VIS ID
TVIS30001063
Fusion event
HIV-SRSF3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
End
36569057/36600978 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1236/Upstream/936189; hsa-mir-10398/Downstream/21458;
Nearest cancer related gene
SRSF3(OG, No orient, 0)
Target sequence
ATTCCCATTAACTAAGCCACCTGGAAAAGTTTAGGAATAGCAGAAACACTGCCATTTCTAAGAACGTAGCCTAAAAAGGTAGTCATTTACCTGCTCCGGCTGCGAGAGAAGCTTCTCCTTCTTGGAGATCTAAAAGCAGAAACAGGAAAATTAGGCTCATCATCAATTAGTATTTATGGCGTGAGGCATTTCCCAACTTTTCAATCTCACTGTTGGGCCCAGTGAATGTGCCGAAGAACTGGCACCCATCGTCCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate