Basic Information
VIS ID
TVIS30001066
Fusion event
HIV-TNRC6A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
End
24783264/24771708 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-361-5p ; hsa-mir-148a-3p ; hsa-let-7d-5p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-30c-5p ; hsa-mir-23a-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-450a-2-3p ; hsa-mir-570-3p ; hsa-mir-3123 ; hsa-mir-3148 ; hsa-mir-3662 ; hsa-mir-3678-3p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-4668-5p ; hsa-mir-4796-3p ; hsa-mir-6124 ; hsa-mir-30c-2-3p ; hsa-mir-23b-3p ; hsa-mir-30b-3p ; hsa-mir-122-5p ; hsa-mir-130a-5p ; hsa-mir-30c-1-3p ; hsa-mir-887-5p ; hsa-mir-3121-3p ; hsa-mir-23c ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3935 ; hsa-mir-3689c ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6782-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-548e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-6077 ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-193b-5p ; hsa-mir-548n ; hsa-mir-548t-5p ; hsa-mir-3170 ; hsa-mir-4259 ; hsa-mir-4260 ; hsa-mir-3668 ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-5094 ; hsa-mir-5572 ; hsa-mir-548az-5p ; hsa-mir-6737-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6855-5p ; hsa-mir-7852-3p ; hsa-mir-4252 ; hsa-mir-4482-3p ; hsa-mir-224-5p ; hsa-mir-299-5p ; hsa-mir-409-3p ; hsa-mir-652-3p ; hsa-mir-8074 ; hsa-mir-6083 ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-130a-3p ; hsa-mir-185-5p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-302b-5p ; hsa-mir-302d-5p ; hsa-mir-373-5p ; hsa-mir-382-3p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-616-5p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-4306 ; hsa-mir-3666 ; hsa-mir-4468 ; hsa-mir-4644 ; hsa-mir-371b-5p ; hsa-mir-4756-3p ; hsa-mir-5584-5p ; hsa-mir-5739 ; hsa-mir-6501-3p ; hsa-mir-6715b-3p ; hsa-mir-7150 ; hsa-mir-4307 ; hsa-mir-369-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-4528 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6076 ; hsa-mir-6797-3p ; hsa-mir-577 ; hsa-mir-607 ; hsa-mir-3163 ; hsa-mir-3671 ; hsa-mir-3942-3p ; hsa-mir-5000-5p ; hsa-mir-7-5p ; hsa-mir-2052 ; hsa-mir-5197-3p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-190a-5p ; hsa-mir-190b ; hsa-mir-1297 ; hsa-mir-4465 ; hsa-mir-5697 ; hsa-mir-374b-3p ; hsa-mir-6748-5p ; hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-582-5p ; hsa-mir-2117 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-3934-3p ; hsa-mir-548v ; hsa-mir-6804-5p ; hsa-mir-139-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-8070 ; hsa-mir-3127-5p ; hsa-mir-5100 ; hsa-mir-6823-5p ; hsa-mir-205-3p ; hsa-mir-4795-3p ; hsa-mir-3200-5p ; hsa-mir-33a-3p ; hsa-mir-4276 ; hsa-mir-922 ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-2467-3p ; hsa-mir-4272 ; hsa-mir-8055 ; hsa-mir-138-2-3p ; hsa-mir-5096 ; hsa-mir-6735-3p ; hsa-mir-6878-3p ; hsa-mir-6513-5p ; hsa-mir-5002-5p ; hsa-mir-302c-5p ; hsa-mir-182-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-3134 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-372-5p ; hsa-mir-371a-5p
Nearest miRNA
hsa-mir-1225/Upstream/568477; hsa-mir-11401/Downstream/1253529;
Target sequence
ACTATATCTCGTAACACTGCATATGCAAAAACAGGCAGTGGGCCAGATTTCACTTGCAGACTGTAGTTTTCCAAACTCTGCTTTATCAAATATAATTTACCAAAATAGGCTCACAGAGGAATAGAAGGTCCTATAGTATAACAGCAGAAACTCTGAAAGGGTCTCCCAAGATTTATCCCTCCAAAACACACCAGGAATACAAAAACAAAAAACCAGCTTCAGCAGCAGATGTCTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate