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TVIS30001067
Basic Information
VIS ID
TVIS30001067
Fusion event
HIV-TNRC6A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
24783029/24771708 (Hg38)
End
24783264/24771708 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
TNRC6A
miRNAs that regulate target gene
hsa-mir-30a-5p
;
hsa-mir-361-5p
;
hsa-mir-148a-3p
;
hsa-let-7d-5p
;
hsa-mir-484
;
hsa-mir-320a
;
hsa-mir-30c-5p
;
hsa-mir-23a-3p
;
hsa-mir-520g-3p
;
hsa-mir-520h
;
hsa-mir-450a-2-3p
;
hsa-mir-570-3p
;
hsa-mir-3123
;
hsa-mir-3148
;
hsa-mir-3662
;
hsa-mir-3678-3p
;
hsa-mir-3919
;
hsa-mir-3925-5p
;
hsa-mir-4668-5p
;
hsa-mir-4796-3p
;
hsa-mir-6124
;
hsa-mir-30c-2-3p
;
hsa-mir-23b-3p
;
hsa-mir-30b-3p
;
hsa-mir-122-5p
;
hsa-mir-130a-5p
;
hsa-mir-30c-1-3p
;
hsa-mir-887-5p
;
hsa-mir-3121-3p
;
hsa-mir-23c
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3935
;
hsa-mir-3689c
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6782-3p
;
hsa-mir-6788-5p
;
hsa-mir-1273h-5p
;
hsa-mir-548e-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30e-5p
;
hsa-mir-1252-3p
;
hsa-mir-3646
;
hsa-mir-6077
;
hsa-mir-3122
;
hsa-mir-3913-5p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-193b-5p
;
hsa-mir-548n
;
hsa-mir-548t-5p
;
hsa-mir-3170
;
hsa-mir-4259
;
hsa-mir-4260
;
hsa-mir-3668
;
hsa-mir-3942-5p
;
hsa-mir-4703-5p
;
hsa-mir-5094
;
hsa-mir-5572
;
hsa-mir-548az-5p
;
hsa-mir-6737-5p
;
hsa-mir-6812-5p
;
hsa-mir-6819-5p
;
hsa-mir-6855-5p
;
hsa-mir-7852-3p
;
hsa-mir-4252
;
hsa-mir-4482-3p
;
hsa-mir-224-5p
;
hsa-mir-299-5p
;
hsa-mir-409-3p
;
hsa-mir-652-3p
;
hsa-mir-8074
;
hsa-mir-6083
;
hsa-mir-17-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-130a-3p
;
hsa-mir-185-5p
;
hsa-mir-106b-5p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-302b-5p
;
hsa-mir-302d-5p
;
hsa-mir-373-5p
;
hsa-mir-382-3p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-518a-5p
;
hsa-mir-527
;
hsa-mir-616-5p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-4306
;
hsa-mir-3666
;
hsa-mir-4468
;
hsa-mir-4644
;
hsa-mir-371b-5p
;
hsa-mir-4756-3p
;
hsa-mir-5584-5p
;
hsa-mir-5739
;
hsa-mir-6501-3p
;
hsa-mir-6715b-3p
;
hsa-mir-7150
;
hsa-mir-4307
;
hsa-mir-369-3p
;
hsa-mir-374a-5p
;
hsa-mir-374b-5p
;
hsa-mir-4528
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-6076
;
hsa-mir-6797-3p
;
hsa-mir-577
;
hsa-mir-607
;
hsa-mir-3163
;
hsa-mir-3671
;
hsa-mir-3942-3p
;
hsa-mir-5000-5p
;
hsa-mir-7-5p
;
hsa-mir-2052
;
hsa-mir-5197-3p
;
hsa-mir-26a-5p
;
hsa-mir-26b-5p
;
hsa-mir-190a-5p
;
hsa-mir-190b
;
hsa-mir-1297
;
hsa-mir-4465
;
hsa-mir-5697
;
hsa-mir-374b-3p
;
hsa-mir-6748-5p
;
hsa-mir-6739-3p
;
hsa-mir-4677-5p
;
hsa-mir-7156-5p
;
hsa-mir-4273
;
hsa-mir-582-5p
;
hsa-mir-2117
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-4533
;
hsa-mir-3934-3p
;
hsa-mir-548v
;
hsa-mir-6804-5p
;
hsa-mir-139-5p
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-8070
;
hsa-mir-3127-5p
;
hsa-mir-5100
;
hsa-mir-6823-5p
;
hsa-mir-205-3p
;
hsa-mir-4795-3p
;
hsa-mir-3200-5p
;
hsa-mir-33a-3p
;
hsa-mir-4276
;
hsa-mir-922
;
hsa-mir-6857-5p
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-6810-5p
;
hsa-mir-143-5p
;
hsa-mir-3944-5p
;
hsa-mir-2467-3p
;
hsa-mir-4272
;
hsa-mir-8055
;
hsa-mir-138-2-3p
;
hsa-mir-5096
;
hsa-mir-6735-3p
;
hsa-mir-6878-3p
;
hsa-mir-6513-5p
;
hsa-mir-5002-5p
;
hsa-mir-302c-5p
;
hsa-mir-182-5p
;
hsa-mir-96-5p
;
hsa-mir-1271-5p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-3134
;
hsa-mir-8082
;
hsa-mir-4534
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
Nearest miRNA
hsa-mir-1225/Upstream/568477; hsa-mir-11401/Downstream/1253529;
Nearest TSS
ENST00000527434/Upstream/41995;
ENST00000568903/Downstream/5540;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/41227
,
chr16-CpG: 66/Downstream/243038
Target sequence
ACTATATCTCGTAACACTGCATATGCAAAAACAGGCAGTGGGCCAGATTTCACTTGCAGACTGTAGTTTTCCAAACTCTGCTTTATCAAATATAATTTACCAAAATAGGCTCACAGAGGAATAGAAGGTCCTATAGTATAACAGCAGAAACTCTGAAAGGGTCTCCCAAGATTTATCCCTCCAAAACACACCAGGAATACAAAAACAAAAAACCAGCTTCAGCAGCAGATGTCTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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