Basic Information
VIS ID
TVIS30001074
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
70341305/70114173 (Hg38)
End
70341960/70114173 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2E
Nearest miRNA
hsa-mir-1301/Upstream/1010418; hsa-mir-10b/Downstream/138745;
Nearest TSS
ENST00000437798/Upstream/24452; ENST00000422380/Downstream/11144;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/25815, chr2-CpG: 19/Downstream/10010
Nearby gene
LINC01816(No orient, 9863)
Target sequence
ACCACCATGCCCCTGGCCCTTCTGTAGAGGGGGCTTTTAAAGAGATAAAACAAACAAAAATCTCAAGTAGGAGAAGTATTGAAACCTTTGATTCCTAGAGAAGATGGAGAAAGAAAGGATTCCTGGTTTAACAAAATGTTAAATGTAGTGAAATTTAAAGTACCCTAATATCACCAATGCCCAGAAGCCTCAGCCATCTGTCACACTGAGGGCTAGGAAATGAGCAAAAATGCCTCTGTGGGACCACAAGAAATA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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