Basic Information
VIS ID
TVIS30001076
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42383737/41856470 (Hg38)
End
42384441/41856470 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1265/Upstream/6215218; hsa-mir-107/Downstream/1141093;
Nearest TSS
ENST00000439456/Upstream/3403289; ENST00000442306/Downstream/328869;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2913364, chr10-CpG: 184/Downstream/254563
Target sequence
GAATGGAATTGTCATCAAATGGAATTCAAAGGAATCATCATGAAATGGAACCGAATGGAATCATCATTGAATGGAAATGAAAGCAGTCATCATCTAATGGAATCGCATGGAATCATCATCAAATGGAATCGAATGGAATCATCATCAAATGGAATCTAATGGAATCATTGAACGGAATTGAATGGAATCGTCATCGAATGAATTGAGTGCAATCATCGAATGGTCTCGAAAGGAATAATCTTCAAATGGAAAGGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate