Basic Information
VIS ID
TVIS30001081
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
27203019/28876001 (Hg38)
End
27203631/28876001 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/14271; hsa-mir-10226/Downstream/514661;
Nearest TSS
ENST00000595228/Upstream/14035; ENST00000579673/Downstream/6658;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/20700, chr17-CpG: 67/Downstream/20986
Nearby gene
FLOT2(No orient, 3338)
Target sequence
GTAGAGCCTATTCTTCCTTCCCTTGAAACTGGTGGGACTTTTGTGGCTATTCAGGCCAATAAAGAGTATTGCAGAAGTGACATTATGTGACTTCTGAGTTTAGATCACAAACGATGACAAAGCCTGTGCTTTATTTGCTGGAATACTCTCTCTTTAAGCCTTTAGCCACCATGTAAGCAGTATGACTGTTCTGAGGGCACTGTACTGTAAGGAAGCCCAAACAGAGGGACCACAGGGTTGGGCCCTGGCTACATG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate