Basic Information
VIS ID
TVIS30001084
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
23896689/23570199 (Hg38)
End
23897279/23570199 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/525827; hsa-mir-101-1/Downstream/358871;
Nearest TSS
ENST00000473358/Upstream/10405; ENST00000612756/Downstream/11296;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1625, chr1-CpG: 17/Downstream/121666
Nearby gene
ID3(No orient, 10404)
Target sequence
CTGAGTAACTGGAACCACAGATGCGTGCCACCAAGCCCGGCTCATTTTAAAATTATTTGTAGAGACAGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAAACCCTGGACTCAAGCTATCCTCCCACCTCAACCTCTCAAAGTGTTGGGATTACAGGTGTGAGCCACTGTATCTGGCCTTAAAATTAATTTCAGTAATATACTTTACCTAATCCAATATATTCAAAACATTATTTCAACATGTGATGAACACAGAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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