Basic Information
VIS ID
TVIS30001097
Fusion event
HIV-LOC107986762 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
5646407/5606776 (Hg38)
End
5647316/5606776 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
LOC107986762
Nearest miRNA
hsa-mir-339/Upstream/110859; hsa-mir-10399/Downstream/105064;
Nearest TSS
ENST00000635602/Upstream/3904; ENST00000416608/Downstream/43239;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1265, chr7-CpG: 22/Downstream/697
Nearby gene
FSCN1(No orient, 120)
Target sequence
GAGGCCGTGGCTCCAGTGGGTGCTCCGGAGCTCGTGGGCCCAGCACACCTCCTTAAGCGGGGGATGGAGCGCTGGGAGGGGGTGGACTGTGGCCCATGCGACCCCCAGAGCCATTAGGAGGAGTTCTGTGGTGAGAAGTGGCTGTGGCTCCTCGTAGGCTACGTCCACCATGCGGGGGACCTCGGGGGTGTCTGGCGGTGGCACGCTGGATGTTGAGAAGGCGCAGCCCAGGGAACACTCAAACCAGGAGACCCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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