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TVIS30001101
Basic Information
VIS ID
TVIS30001101
Fusion event
HIV-AKAP13 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
86107553/85564322 (Hg38)
End
86108447/85564322 (Hg38)
Orient
+
Location type
Intronic
Target gene
AKAP13
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-423-5p
;
hsa-mir-193b-3p
;
hsa-mir-484
;
hsa-mir-149-5p
;
hsa-mir-16-5p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-8074
;
hsa-mir-6778-3p
;
hsa-mir-4287
;
hsa-mir-4685-3p
;
hsa-mir-1281
;
hsa-mir-3667-3p
;
hsa-mir-6832-3p
;
hsa-mir-183-5p
Nearest miRNA
hsa-mir-10393/Upstream/183660; hsa-mir-11181/Downstream/206174;
Nearest TSS
ENST00000557528/Upstream/8876;
ENST00000560340/Downstream/15856;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/182873
,
chr15-CpG: 20/Downstream/194396
Nearest cancer related gene
AKAP13
(OG, No orient, 0)
Target sequence
GGTTACATTTGCTTTATCTGTGTGTGTATACATATACATATATAGAATTTTACTGAAGTCTTTGAGAGTAAGTTGCAGAATCATGACCTTCTGTTCCTAAATATTTCAGCATATATTTCCTAAGAACAAGGACAGTCAATACAGTAACAGTGCATTTATCAAAATTAGTAATTTATCATTAATACAATAATCTAATATATAGTAGTTTATATTCTACTTTTCACCATCTGCTTAATAGTGTTCTTTTAAGTATTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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