Basic Information
VIS ID
TVIS30001101
Fusion event
HIV-AKAP13 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
End
86108447/85564322 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/183660; hsa-mir-11181/Downstream/206174;
Nearest cancer related gene
AKAP13(OG, No orient, 0)
Target sequence
GGTTACATTTGCTTTATCTGTGTGTGTATACATATACATATATAGAATTTTACTGAAGTCTTTGAGAGTAAGTTGCAGAATCATGACCTTCTGTTCCTAAATATTTCAGCATATATTTCCTAAGAACAAGGACAGTCAATACAGTAACAGTGCATTTATCAAAATTAGTAATTTATCATTAATACAATAATCTAATATATAGTAGTTTATATTCTACTTTTCACCATCTGCTTAATAGTGTTCTTTTAAGTATTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate