Basic Information
VIS ID
TVIS30001102
Fusion event
HIV-ANKRD13C integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
70813869/70348186 (Hg38)
End
70813966/70348186 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ANKRD13C
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-122-5p ; hsa-mir-181a-5p ; hsa-mir-374a-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p ; hsa-mir-219a-2-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2164576; hsa-mir-11399/Downstream/719445;
Nearest TSS
ENST00000473358/Upstream/23229; ENST00000486110/Downstream/6536;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/142427, chr1-CpG: 84/Downstream/5864
Target sequence
AAAAGGAAGATACGAGATTTATACAGAATAAACCAAAATAAACATACTGTATGGCCATGAAATAGATTATCCTATCTTCTCAATCCTCAAATGCACATTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate