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VISDB
Viral Integration Site DataBase
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TVIS30001105
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
89784136
89926529
90296908
90014549
90022657
90033150
90038748
89997029
90000167
90028300
90030590
90003106
90005275
89988882
89991035
90039325
90041111
90008200
90009910
90025225
90026471
90007016
90007409
90012365
90012644
90000302
90000451
90040522
Basic Information
VIS ID
TVIS30001105
Fusion event
HIV-BACH2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
90750241/90040522 (Hg38)
End
90750479/90040522 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
BACH2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-29c-3p
;
hsa-mir-615-3p
;
hsa-mir-8064
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6083
;
hsa-mir-5011-5p
;
hsa-mir-656-3p
;
hsa-mir-410-3p
;
hsa-mir-3942-3p
;
hsa-mir-1324
;
hsa-mir-8485
;
hsa-mir-6797-3p
;
hsa-mir-6076
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-6749-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-2355-5p
;
hsa-mir-15b-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6832-3p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-5695
;
hsa-mir-3145-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-4791
;
hsa-mir-3201
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-142-5p
Nearest miRNA
hsa-mir-10398/Upstream/11501213; hsa-mir-1202/Downstream/272220;
Nearest TSS
ENST00000381078/Upstream/31695;
ENST00000569865/Downstream/177723;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/152588
,
chr6-CpG: 227/Downstream/254554
Target sequence
GGAATTGAACTCAAGAACTCCTTAAGATGTAAATCTTTATTCTTGTAAATAAATGAAACTGTTTTAAAATCCTCCTGAGATGAAGAGAAAAAACAAAGATGTGAATAAATGGAAAGACAATCCATGTCCTTGGACAGAAAACCTCAACATCACAAATTTAATGTGAATGCAGTAAAAATACCAACAGAATATTTTGTAACCAAACAAGCTGATGCTGAAGTTCATGTAAAAAAAAAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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