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TVIS30001110
Basic Information
VIS ID
TVIS30001110
Fusion event
HIV-BTRC integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
103305127/101545370 (Hg38)
End
103305698/101545370 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
BTRC
miRNAs that regulate target gene
hsa-mir-183-5p
;
hsa-mir-10a-5p
;
hsa-mir-193b-3p
;
hsa-mir-320a
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-mir-15a-5p
;
hsa-let-7e-5p
;
hsa-mir-195-5p
;
hsa-mir-497-5p
;
hsa-mir-4271
;
hsa-mir-548au-3p
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-449c-5p
;
hsa-mir-34b-5p
;
hsa-mir-2682-5p
;
hsa-mir-3974
;
hsa-mir-3714
;
hsa-mir-548an
;
hsa-mir-7155-3p
;
hsa-mir-3136-3p
;
hsa-mir-4722-5p
;
hsa-mir-5008-5p
;
hsa-mir-605-3p
;
hsa-mir-4692
;
hsa-mir-4514
;
hsa-mir-4762-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4695-5p
;
hsa-mir-554
;
hsa-mir-4709-5p
;
hsa-mir-624-5p
;
hsa-mir-101-3p
;
hsa-mir-6884-5p
;
hsa-mir-421
;
hsa-mir-3115
;
hsa-mir-505-3p
;
hsa-mir-493-3p
;
hsa-mir-6871-5p
;
hsa-mir-15b-5p
;
hsa-mir-10a-3p
Nearest miRNA
hsa-mir-107/Upstream/570286; hsa-mir-1307/Downstream/56047;
Nearest TSS
ENST00000439456/Upstream/9986;
ENST00000470165/Downstream/25190;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/190713
,
chr10-CpG: 53/Downstream/21049
Target sequence
GTACACATTAAGGATTGTTAGGTCTTCTTGGAGAACTGGCCCCTTTATCCTTATACAACACTTCTCTTTATCCCTGATAATATTCTTTGCTCTGAGGTTTGCTCTCTCTCTAATTAATACAGCTACCCCAACTTTCTTCTGACTAGTGTTAGAATGGTCCATCAGGGCTAGGGGTGCCATAACAAAGTATGGCATACACTAGGGGGCTCAAAAAATAGAAATTAATTTCCCTACAGTCTGGAGACTAGAATTCTA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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