Basic Information
VIS ID
TVIS30001117
Fusion event
HIV-SMG1P2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
30292320/30280999 (Hg38)
End
30293128/30280999 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SMG1P2
Nearest miRNA
hsa-mir-1225/Upstream/681734; hsa-mir-11401/Downstream/222920;
Nearest TSS
ENST00000527434/Upstream/26489; ENST00000563252/Downstream/73935;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/57682, chr16-CpG: 90/Downstream/53732
Target sequence
AATATTAAAAATCTATATATATTCTTCTATGAAACACTGGGGATGGGGGATTGGGGTTTTTCATGTATTTCTTTTCAGAAAGAATAAGAAAGCCTAGATTAAATAATAAAACCAAATTATAAGGTGTTTGACAGTAAAGAAGCTGCTCTACCTCACCTCTATAATCCACATTTTTAAAAATTTTTTGTAATTCACATTTCTTATTCTCAAATTATAAAGGCAAATTAACAAAGTTAGGAATAGTTAATACTATAT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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