VISDB Viral Integration Site DataBase

VIS ID

TVIS30001120

Fusion event

HIV-MDC1 integration

Validated

Yes

Detection method

QiaQuick PCR and Sequencing

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.33

Reference genome

Start

End

30681185/30712509 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-505-3p ; hsa-mir-324-5p ; hsa-mir-361-5p ; hsa-mir-18a-5p ; hsa-mir-17-3p ; hsa-mir-335-3p ; hsa-mir-4474-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-6815-3p ; hsa-mir-2115-5p ; hsa-mir-627-3p ; hsa-mir-4729 ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-605-5p ; hsa-mir-1253 ; hsa-mir-185-5p ; hsa-mir-3180-5p ; hsa-mir-33a-3p ; hsa-mir-411-5p ; hsa-mir-4306 ; hsa-mir-4307 ; hsa-mir-4644 ; hsa-mir-4768-3p ; hsa-mir-516a-3p ; hsa-mir-516b-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-665 ; hsa-mir-7162-5p

Nearest miRNA

hsa-mir-3143/Upstream/128092; hsa-mir-10398/Downstream/178374;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/21261, chr6-CpG: 52/Downstream/4550

Nearest cancer related gene

MDC1(TSG, No orient, 0)

Target sequence

GGTATCCCTTCCAGGGAAATAAATTCTATAGACTCTCTTTTCTTCCCTTCACAGTGATGAAGAGGGGCATTCCCCGGTCCTGGGCGGCCTTGGGCCGCCTTTTGCCTTCAATTTGAACAGTGACACAGATGTGGAAGAAGGTCAGCAACCAGCCACAGAGGAGGCCTCCTCAGCTGCCAGAAGAGGTGCCACTGTAGAGGCAAAGCAGTCTGAAGCTGAAGTTGTAACTGAAATCCAGCTTGAAAAGGATCAGCC