Basic Information
VIS ID
TVIS30001135
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
138248668/137927531 (Hg38)
End
138249613/137927531 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/2688275; hsa-mir-1202/Downstream/507682;
Nearest TSS
ENST00000381078/Upstream/51693; ENST00000434437/Downstream/17835;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/59527, chr6-CpG: 65/Downstream/179520
Nearby gene
TNFAIP3(No orient, 44217)
Nearest cancer related gene
TNFAIP3(TSG, No orient, 44217)
Target sequence
AATACCCTTTGTGAAAACCACAAAATAGGCAATTTGAAAAGTAGAGAGAACTCTGAAGAGGAAAAAAGGTCCCTTGCCATTTTACTACTTTCAGCATTTTAATTAAAATGTATTTTTGTCAATGCAATGGTTGTTTCAGACATTTTAAGAAAACATCTTGATTCCAAACCCCAGGGTAAATTAAGTCAATAAACTTTTGAAGACTTGTGCCATGCTGCAGATGGACTTTAAAAGCCACTGGGGGGTGGGGAGAAT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate