Basic Information
VIS ID
TVIS30001136
Fusion event
HIV-KIF28P integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
246937957/246774655 (Hg38)
End
246938827/246774655 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
KIF28P
Nearest miRNA
hsa-mir-101-1/Upstream/3428400; hsa-mir-3124/Downstream/427312;
Nearest TSS
ENST00000473358/Upstream/2354; ENST00000474792/Downstream/75194;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/49929, chr1-CpG: 34/Downstream/14257
Nearby gene
SCCPDH(No orient, 6517)
Target sequence
GAGGTCAGGGATGCCAGCTTTCTTGACCTCTGTCCTTTAGGTTCTAGCCAGTGCAGTAAGGAAAAGAAATACAAAGTATGACTGGAAAGGAAAGAAAAGTAATTACAATAATAGCATACACTTATGTAACACTTACAACCTGCTTTACATTTACTGTCTCAATTCTCACAGCAACCCTATGAGGCAGGTACTATTATTCACCTTATTTTACAGTTCATGGAACGTGTCTAAAGACACATGACTCATCTGTGGCAG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate