Basic Information
VIS ID
TVIS30001138
Fusion event
HIV-ACSF3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89173676/89107268 (Hg38)
End
89174224/89107268 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACSF3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-11401/Upstream/390931;
Nearest TSS
ENST00000527434/Upstream/4572; ENST00000562204/Downstream/4933;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/5685, chr16-CpG: 18/Downstream/28
Target sequence
GGTGTGTGAAACATGCGGCCACGTTTGAGAACTCTTCCGCAGTTTCCACTGAAATGAAACATACATCTAGCCTGTGAGCCGGCACTGGGAGTTGCGGATCCGAGGGAACTGTCCACAGGGACATCTGTGTGAGAATGTTCATAGCAACCGTGACTTCTAATAGCCACAAACTGAAAACAATCTCAAGTCCTTCAAGAGCAGAATGGATAAGCGCACTGTGGCTTCTGCACACCAGGAAATACAACACAGCAACGT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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