Basic Information
VIS ID
TVIS30001139
Fusion event
HIV-ACSF3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89173734/89107326 (Hg38)
End
89174224/89107326 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACSF3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-11401/Upstream/390989;
Nearest TSS
ENST00000527434/Upstream/4630; ENST00000562204/Downstream/4875;
Nearest CpG islands
chr16-CpG: 18/Target, None/Upstream, None/Downstream
Target sequence
GGTGTGTGAAACATGCAGCCACGTTTGAGAACTCTTCCGCAGTTTCCACTGAAATGAAACATACATCTAGCCTGTGAGCCGGCACTGGGAGGTGCGGATCCAAGGGAACTGTCCACAGGGACATCTGTGTGAGAATGTTCATAGCAACCGTGACTTCTAATAGCCACAAACTGAAAACAATCTCAAGTCCTTCAAGAGCAGAATGGATAAGCGCACTGTGGCTTCTGCACACCAGGAAATACAACACAGCAACGT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate