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TVIS30001145
Basic Information
VIS ID
TVIS30001145
Fusion event
HIV-CAPRIN1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
34086507/34064960 (Hg38)
End
34087098/34064960 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
CAPRIN1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-34a-5p
;
hsa-mir-21-5p
;
hsa-mir-1296-5p
;
hsa-mir-92b-3p
;
hsa-mir-484
;
hsa-mir-222-3p
;
hsa-mir-92a-3p
;
hsa-mir-3678-3p
;
hsa-mir-2467-3p
;
hsa-mir-223-3p
;
hsa-mir-6868-3p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-589-3p
;
hsa-mir-548c-3p
;
hsa-mir-587
;
hsa-mir-3117-3p
;
hsa-mir-1197
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6509-5p
;
hsa-mir-4677-5p
;
hsa-mir-6844
;
hsa-mir-6873-3p
;
hsa-mir-6867-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-331-5p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-567
;
hsa-mir-942-5p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-6832-3p
;
hsa-mir-4469
;
hsa-mir-4678
;
hsa-mir-452-3p
;
hsa-mir-6777-3p
;
hsa-mir-483-3p
;
hsa-mir-6715a-3p
;
hsa-mir-141-5p
;
hsa-mir-497-3p
;
hsa-mir-33b-5p
;
hsa-mir-33a-5p
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-4317
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-1-5p
;
hsa-mir-129-5p
;
hsa-mir-2113
;
hsa-mir-5010-3p
;
hsa-mir-758-3p
Nearest miRNA
hsa-mir-210/Upstream/5587412; hsa-let-7a-2/Downstream/876877;
Nearest TSS
ENST00000527297/Upstream/9222;
ENST00000528948/Downstream/25066;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/11804
,
chr11-CpG: 60/Downstream/40321
Target sequence
GGCCCCAAACCAGCAACATCAGCATCAACTGGCACCTTGTTAGAAACACAAATTCTCAGGCACTACCCCAGACCTACTGAATCAGAAACTCAGTGGTGGCTGGGGGAACCCAGCAATTTGTAGTTGGTATTGAGTCTTCTGGGTGATTCTGATGCATGCTTAAGTTTGAGAAACACTCATCTCGTTCAAATACATTGTAATTAACTTGTAATAGCCCAGTAGAACCTGGAAATAAATTATTCTGAATCAAACATA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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