Basic Information
VIS ID
TVIS30001148
Fusion event
HIV-CYP3A5 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
End
99265297/99667462 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/258198; hsa-mir-10399/Downstream/426098;
Target sequence
ATAGTCCAGCCCCAAGTTGGGAAAAGTAATTATCCCTTTCTTTTTCCTTCTATTTATGGAATAAAAAATTAAGAGAAAAGAATTTTCAAGGAAATTGCATTATTCCTTCAAAACAGGTTTCTAGTCTTTAAGTATTACCTACTTTTCAAAAAAAAACCACCACATCATGGCATCCCTTTTTCAAATTGCCCATGCTGTAGGTGTATTAAAGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate