Home
Browse
Prime browse
Clustered VIS browse
Search
Curation
Gene
Target gene
All
Oncogene
Tumor suppressor gene
Nearby gene
All
Oncogene
Tumor suppressor gene
MicroRNA
RNA-interaction
ncRNA
Host2Host
Host2Virus
Virus2Host
• miRNA
Host2Host
Host2Virus
Virus2Host
• lncRNA
Host2Host
Host2Virus
Virus2Host
Download
Statistics
Help
VISDB
Viral Integration Site DataBase
Homepage
Prime VIS Browse Options
TVIS30001148
Basic Information
VIS ID
TVIS30001148
Fusion event
HIV-CYP3A5 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99265085/99667462 (Hg38)
End
99265297/99667462 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
CYP3A5
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-599
;
hsa-mir-3161
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-4254
;
hsa-mir-3690
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-3191-5p
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-2115-5p
;
hsa-mir-6728-3p
;
hsa-mir-4438
Nearest miRNA
hsa-mir-10525/Upstream/258198; hsa-mir-10399/Downstream/426098;
Nearest TSS
ENST00000635602/Upstream/3880;
ENST00000608397/Downstream/9114;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/50200
,
chr7-CpG: 76/Downstream/251517
Target sequence
ATAGTCCAGCCCCAAGTTGGGAAAAGTAATTATCCCTTTCTTTTTCCTTCTATTTATGGAATAAAAAATTAAGAGAAAAGAATTTTCAAGGAAATTGCATTATTCCTTCAAAACAGGTTTCTAGTCTTTAAGTATTACCTACTTTTCAAAAAAAAACCACCACATCATGGCATCCCTTTTTCAAATTGCCCATGCTGTAGGTGTATTAAAGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
Download
Curate