Basic Information
VIS ID
TVIS30001150
Fusion event
HIV-MALAT1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
End
65273197/65504842 (Hg38)
Orient
-
Location type
ncRNA_exonic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/60285; hsa-let-7a-2/Downstream/131468;
Nearest cancer related gene
MALAT1(OG, No orient, 0)
Target sequence
CAGGCAAATTAATGGCCTTTTCTAACATAGTTCAACCCACCAAAGACCTCGACACCATCGTTACCTTGAAACCGATTATGGATCATGCCCACAAGGATCCAAGCTACTGGCTGCATCGAGGTGAGGGGTGAAGGGTCTGTGCTAGATCAAAAGGCACGGGGTGGCGATGTGGCAGAGAAGTTGCTTGTGGGGAGACCTTGCTTTTAACAGGCTTCTGGAAAAGCTAGGGAAAAGTGGTTGCCCGCTTTCCCCCTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate