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TVIS30001151
Basic Information
VIS ID
TVIS30001151
Fusion event
HIV-MAP7 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
136841583/136520445 (Hg38)
End
136842476/136520445 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAP7
miRNAs that regulate target gene
hsa-mir-130b-3p
;
hsa-mir-93-5p
;
hsa-mir-19b-3p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-3613-3p
;
hsa-let-7c-3p
;
hsa-mir-6866-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-4766-3p
;
hsa-mir-548p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-3646
;
hsa-mir-106a-5p
;
hsa-mir-526b-3p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-20a-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-130a-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-301b-3p
;
hsa-mir-3666
;
hsa-mir-301a-3p
;
hsa-mir-493-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-5692a
;
hsa-mir-4436b-5p
;
hsa-mir-4284
;
hsa-mir-4772-3p
;
hsa-mir-4518
;
hsa-mir-1266-5p
;
hsa-mir-3664-3p
;
hsa-mir-1304-3p
;
hsa-mir-6890-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-4793-5p
;
hsa-mir-205-3p
;
hsa-mir-218-1-3p
;
hsa-mir-3606-3p
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-659-3p
;
hsa-mir-6758-3p
;
hsa-mir-9-5p
Nearest miRNA
hsa-mir-10398/Upstream/1281189; hsa-mir-1202/Downstream/1914768;
Nearest TSS
ENST00000381078/Upstream/53570;
ENST00000607749/Downstream/5538;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/159310
,
chr6-CpG: 160/Downstream/29243
Target sequence
GTTTACCTTTGTTTCATAATGTTCCATTTACTCTGAAAAGTACAGGGTATAAAGAGGAGTGAGTCCTGGCCCTTACAAAGCTTACAGTGTCAAGAAGGACATGGGTGTGTGCATGGATGATTTCATTACACTGATGTAAGTCAGTAATGGATTTACAGTGCGGAAGGAGCACAGTGAGGGGCTGCCCTTTGTGCCAGGAATGAGGAGGCTGGGAGCGAGAGAGGAGGTTTCCTGCAGATGGCACCCAAGGAAAGT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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