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TVIS30001152
Basic Information
VIS ID
TVIS30001152
Fusion event
HIV-MAPK1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
22169409/21815120 (Hg38)
End
22169594/21815120 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAPK1
miRNAs that regulate target gene
hsa-mir-199a-3p
;
hsa-mir-28-5p
;
hsa-mir-335-5p
;
hsa-mir-320a
;
hsa-mir-30a-5p
;
hsa-mir-766-3p
;
hsa-mir-769-5p
;
hsa-mir-92b-3p
;
hsa-mir-15b-5p
;
hsa-let-7b-5p
;
hsa-mir-214-3p
;
hsa-mir-143-3p
;
hsa-mir-132-3p
;
hsa-mir-4643
;
hsa-mir-5190
;
hsa-mir-4253
;
hsa-mir-6862-5p
;
hsa-mir-4796-3p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-378a-3p
;
hsa-mir-181a-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-498
;
hsa-mir-6869-5p
;
hsa-mir-1200
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-4703-3p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-3653-5p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-660-3p
;
hsa-mir-6849-3p
;
hsa-mir-1244
;
hsa-mir-4689
;
hsa-mir-6858-5p
;
hsa-mir-1268b
;
hsa-mir-1268a
;
hsa-mir-585-3p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-6894-5p
;
hsa-mir-6853-5p
;
hsa-mir-3605-5p
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-1273f
;
hsa-mir-4459
;
hsa-mir-4433a-3p
;
hsa-mir-4768-3p
;
hsa-mir-5000-5p
;
hsa-mir-6888-5p
;
hsa-mir-573
;
hsa-mir-3616-5p
;
hsa-mir-185-3p
;
hsa-mir-4741
;
hsa-mir-4675
;
hsa-mir-6813-5p
;
hsa-mir-4795-5p
;
hsa-mir-6085
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-3936
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-301b-3p
;
hsa-mir-3666
;
hsa-mir-4295
;
hsa-mir-454-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-4420
;
hsa-mir-181b-3p
;
hsa-mir-181b-2-3p
;
hsa-mir-6773-3p
;
hsa-mir-668-3p
;
hsa-mir-450a-2-3p
;
hsa-mir-6857-5p
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-6810-5p
;
hsa-mir-2110
;
hsa-mir-6873-3p
;
hsa-mir-6883-3p
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-3927-5p
;
hsa-mir-454-5p
;
hsa-mir-487a-3p
;
hsa-mir-154-3p
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-216b-5p
;
hsa-mir-106a-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-526b-3p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-584-5p
;
hsa-mir-3157-3p
;
hsa-mir-4261
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-18b-3p
;
hsa-mir-6734-3p
;
hsa-mir-371b-3p
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-3614-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-196b-5p
;
hsa-mir-196a-5p
;
hsa-mir-513a-5p
;
hsa-mir-494-3p
;
hsa-mir-499b-3p
;
hsa-mir-499a-3p
;
hsa-mir-4438
;
hsa-mir-5698
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-566
;
hsa-mir-6789-3p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-6786-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-5693
;
hsa-mir-6808-3p
;
hsa-mir-7973
;
hsa-mir-4252
;
hsa-mir-6846-3p
;
hsa-mir-6859-3p
;
hsa-mir-4286
;
hsa-mir-4301
;
hsa-mir-4692
;
hsa-mir-4514
;
hsa-mir-4691-3p
;
hsa-mir-3157-5p
;
hsa-mir-5003-5p
;
hsa-mir-449b-3p
;
hsa-mir-7641
;
hsa-mir-4279
;
hsa-mir-6867-3p
;
hsa-mir-7111-3p
;
hsa-mir-4695-3p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-6777-3p
;
hsa-mir-4639-3p
;
hsa-mir-4761-3p
;
hsa-mir-197-3p
;
hsa-mir-550a-3p
;
hsa-mir-329-3p
;
hsa-mir-9-3p
;
hsa-mir-129-5p
;
hsa-mir-451a
Nearest miRNA
hsa-mir-1286/Upstream/161735; hsa-let-7a-3/Downstream/1007656;
Nearest TSS
ENST00000624155/Upstream/45692;
ENST00000458178/Downstream/52320;
Nearest CpG islands
None/Target,
chr22-CpG: 279/Upstream/78500
,
chr22-CpG: 119/Downstream/51645
Target sequence
GTGGTGCCATCTGGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACTGGTGCCCGTCACCACGCACAGCTAATTTTTTGTATTTTAGTAGAGATAGGGTTTCACCATGTTGGCTAGGATGGTCTCGATCTCCTGACCTCATGATCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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