Basic Information
VIS ID
TVIS30001152
Fusion event
HIV-MAPK1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
End
22169594/21815120 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-199a-3p ; hsa-mir-28-5p ; hsa-mir-335-5p ; hsa-mir-320a ; hsa-mir-30a-5p ; hsa-mir-766-3p ; hsa-mir-769-5p ; hsa-mir-92b-3p ; hsa-mir-15b-5p ; hsa-let-7b-5p ; hsa-mir-214-3p ; hsa-mir-143-3p ; hsa-mir-132-3p ; hsa-mir-4643 ; hsa-mir-5190 ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-4796-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-378a-3p ; hsa-mir-181a-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-498 ; hsa-mir-6869-5p ; hsa-mir-1200 ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4703-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-3653-5p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-6849-3p ; hsa-mir-1244 ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-585-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6894-5p ; hsa-mir-6853-5p ; hsa-mir-3605-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-1273f ; hsa-mir-4459 ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-5000-5p ; hsa-mir-6888-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-185-3p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-6813-5p ; hsa-mir-4795-5p ; hsa-mir-6085 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3936 ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-6773-3p ; hsa-mir-668-3p ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-6873-3p ; hsa-mir-6883-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3927-5p ; hsa-mir-454-5p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-216b-5p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-584-5p ; hsa-mir-3157-3p ; hsa-mir-4261 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-18b-3p ; hsa-mir-6734-3p ; hsa-mir-371b-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-3614-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-196b-5p ; hsa-mir-196a-5p ; hsa-mir-513a-5p ; hsa-mir-494-3p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-4438 ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-6786-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-5693 ; hsa-mir-6808-3p ; hsa-mir-7973 ; hsa-mir-4252 ; hsa-mir-6846-3p ; hsa-mir-6859-3p ; hsa-mir-4286 ; hsa-mir-4301 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4691-3p ; hsa-mir-3157-5p ; hsa-mir-5003-5p ; hsa-mir-449b-3p ; hsa-mir-7641 ; hsa-mir-4279 ; hsa-mir-6867-3p ; hsa-mir-7111-3p ; hsa-mir-4695-3p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6777-3p ; hsa-mir-4639-3p ; hsa-mir-4761-3p ; hsa-mir-197-3p ; hsa-mir-550a-3p ; hsa-mir-329-3p ; hsa-mir-9-3p ; hsa-mir-129-5p ; hsa-mir-451a
Nearest miRNA
hsa-mir-1286/Upstream/161735; hsa-let-7a-3/Downstream/1007656;
Target sequence
GTGGTGCCATCTGGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACTGGTGCCCGTCACCACGCACAGCTAATTTTTTGTATTTTAGTAGAGATAGGGTTTCACCATGTTGGCTAGGATGGTCTCGATCTCCTGACCTCATGATCC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate