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TVIS30001169
Basic Information
VIS ID
TVIS30001169
Fusion event
HIV-MED13 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
60021649/61944288 (Hg38)
End
60021764/61944288 (Hg38)
Orient
+
Location type
UTR3
Target gene
MED13
miRNAs that regulate target gene
hsa-mir-208a-3p
;
hsa-mir-151a-3p
;
hsa-mir-103a-3p
;
hsa-mir-16-5p
;
hsa-mir-1303
;
hsa-mir-30c-5p
;
hsa-mir-196a-5p
;
hsa-mir-17-5p
;
hsa-let-7b-5p
;
hsa-mir-141-3p
;
hsa-mir-200a-3p
;
hsa-mir-495-3p
;
hsa-mir-5688
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-5580-3p
;
hsa-mir-8084
;
hsa-mir-6831-3p
;
hsa-mir-205-5p
;
hsa-mir-5585-5p
;
hsa-mir-548ax
;
hsa-mir-548ao-5p
;
hsa-mir-6811-5p
;
hsa-mir-6511b-5p
;
hsa-mir-5585-3p
;
hsa-mir-4708-5p
;
hsa-mir-1253
;
hsa-mir-153-5p
;
hsa-mir-95-5p
;
hsa-mir-5197-3p
;
hsa-mir-338-5p
;
hsa-mir-5692a
;
hsa-mir-3591-5p
;
hsa-mir-4460
;
hsa-mir-4727-3p
;
hsa-mir-4775
;
hsa-mir-7160-5p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-27b-5p
;
hsa-mir-6718-5p
;
hsa-mir-203b-5p
;
hsa-mir-590-3p
;
hsa-mir-562
;
hsa-mir-140-5p
;
hsa-mir-568
;
hsa-mir-4477a
;
hsa-mir-3163
;
hsa-mir-595
;
hsa-mir-224-5p
;
hsa-mir-4783-5p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
Nearest miRNA
hsa-mir-10226/Upstream/1901183; hsa-mir-1250/Downstream/999927;
Nearest TSS
ENST00000595228/Upstream/16272;
ENST00000635817/Downstream/11475;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/16233
,
chr17-CpG: 101/Downstream/120598
Target sequence
TAAAGTCACTATTAAGTGTATAAAAAGGATACTCTTTTTATGGAAATTCCAAATAAGCACATTTTCCTTCAAATCTCAGACAAGTTTTTTTTTTTTTTTTAAAGAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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