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TVIS30001175
Basic Information
VIS ID
TVIS30001175
Fusion event
HIV-SH3PXD2A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
105573972/103814214 (Hg38)
End
105574923/103814214 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
SH3PXD2A
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-130b-3p
;
hsa-mir-124-3p
;
hsa-mir-93-5p
;
hsa-mir-33a-5p
;
hsa-mir-24-3p
;
hsa-mir-331-3p
;
hsa-let-7b-5p
;
hsa-mir-155-5p
;
hsa-mir-212-5p
;
hsa-mir-377-3p
;
hsa-mir-8485
;
hsa-mir-148a-3p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-6818-5p
;
hsa-mir-6867-5p
;
hsa-mir-1257
;
hsa-mir-642b-3p
;
hsa-mir-642a-3p
;
hsa-mir-6849-3p
;
hsa-mir-425-5p
;
hsa-mir-603
;
hsa-mir-2110
;
hsa-mir-491-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6769a-5p
;
hsa-mir-654-5p
;
hsa-mir-541-3p
;
hsa-mir-486-3p
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-4747-5p
;
hsa-mir-5196-5p
;
hsa-mir-3202
;
hsa-mir-657
;
hsa-mir-3665
;
hsa-mir-6873-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-4639-3p
;
hsa-mir-6875-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4753-3p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-4469
;
hsa-mir-6832-3p
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-5571-5p
;
hsa-mir-342-3p
;
hsa-mir-5003-5p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-3157-5p
;
hsa-mir-5695
;
hsa-mir-6769a-3p
;
hsa-mir-3145-5p
;
hsa-mir-130b-5p
;
hsa-mir-5692a
;
hsa-mir-4643
;
hsa-mir-4717-3p
;
hsa-mir-942-3p
;
hsa-mir-448
;
hsa-mir-153-3p
;
hsa-mir-4672
;
hsa-mir-5689
;
hsa-mir-6768-5p
;
hsa-mir-548o-3p
;
hsa-mir-1323
;
hsa-mir-5096
;
hsa-mir-3614-3p
;
hsa-mir-6803-5p
;
hsa-mir-6751-5p
;
hsa-mir-7109-5p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-561-5p
;
hsa-mir-615-5p
;
hsa-mir-6885-5p
;
hsa-mir-328-5p
;
hsa-mir-6887-5p
;
hsa-mir-6795-5p
;
hsa-mir-3189-3p
;
hsa-mir-6830-5p
;
hsa-mir-6732-5p
;
hsa-mir-4428
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-30e-5p
;
hsa-mir-30d-5p
;
hsa-mir-30c-5p
;
hsa-mir-30a-5p
;
hsa-mir-30b-5p
;
hsa-mir-200c-3p
Nearest miRNA
hsa-mir-107/Upstream/419813; hsa-mir-202/Downstream/233875;
Nearest TSS
ENST00000439456/Upstream/12917;
ENST00000474260/Downstream/41192;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/120742
,
chr10-CpG: 73/Downstream/40539
Target sequence
GTCTTAGAAACCCTTGACTAATTCAAGGTCATGGAGATTTGTGCTATGTTTTCTTCTAAGACTTTAATAGTTTTCTCTCTCGCATTTAGGTCTCTCATCTATTTCAAGTTAATTTTTGTGTGTGATCTGAGGTCCTTCTCATTTTGTACTGAGTCAAACTGAAGAGCCCCCCACCTCCCCAGTTGGCCTGCCACACTTTGCCTTCTGCATTTGGGTCTCAGCTCAAACATCCTCACTCCAGGGAGGCCTCCCCTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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